303 LU RUN CHANG PIAN
Moisten the intestines Tablet – Promoting healthy Large Intestine function since 1231 A.D.

TCM Therapeutic Actions:
Relieves intestinal dryness; relieves blocked bowels; relieves Blood and Yin deficiency; clears Heat in the Lower Warmer and disperses Wind.

TCM Indications:
Blood stagnation in the Large Intestine, constipation, loss of appetite, fatigue.

Modern Indications:
Constipation.

Contraindications:
Contraindicated during pregnancy. Caution in breast-feeding: Rhubarb can pass through breast milk, causing colic and diarrhea in the child. Caution: This formula can become habitual when taken alone. May cause mild abdominal cramping in sensitive patients.

TCM Contraindications:
Not recommended in patients who do not have constipation or blood stagnation. Not for constipation due to excess heat. Use caution with abdominal distention, Spleen deficiency, or diarrhea.

Pharmaceutical Interactions:
May increase anticoagulant and antiplatelet effects; use cautiously with these types of agents as well as thrombolytic agents and low molecular weight heparins. May have estrogen-like activity. May cause potassium loss and increase toxicity of cardiac glycosides. Use cautiously with laxatives, as synergistic effects may cause excessive diarrhea, dehydration, and electrolyte imbalance.

Comments:
For use in patients with chronic constipation due to Yin, Blood, or body fluid deficiency or Heat in the intestines. Not suitable for excess Heat in the intestines. This formula is a mild
laxative and should be used with a primary formula to address the root of the problem. Start with a small dose and increase until smooth bowel movement is achieved. This formula may
be discontinued after primary formula has satisfactorily addressed root problem.

Recommended Usage:
2-3 tablets twice daily with warm water.